The fact that Khamenei was killed during the first strike means there are serious lapse on Iranian intelligence apparatus. While I don't know for sure, it seems like there aissome high level leakage on this end toward the US and Israel. Maybe someone betrayed Khamenei.
Because everyone is talking about this ops for months, intelligence circle all concluded the US is going to strike Iran this week or next, this is not something new or hidden, why you would have a high level meet with people in this calibur, that incharge of C4 and basically is a central leader go out and have a meet, and then let Mossad (not really thinking it's the CIA) know where the meet is going to be.
It only means 2 things. Either Iranian intelligence is worse than keystone cops.......Or someone in high echelofacilitatedte this meeting, leaked the intelligence to Mossad, andthe result is Khamenei being killed.