It does change things, Syria is in a stronger position if the PKK element is removed and the US has left, b/c then there is only 1 front left, towards Suwaida and the Golan. right now there are 3 fronts. Consolidation plus acquisition of resources is always a positive.
It won't be Jolani that initiates the fight, it will be Turkey and the SNA groups. Me personally this fight should have happened 1 year ago, after Assad fell and then Manbij was taken, if it was up to me, Turkey would have intervened and we would have be done with this nuisance. I'm not really sure what the calculation is or what the holdup is, but IMO Turkey has been too passive in letting thing play out, rather than actively shaping it.