Covid-19 News and Discussions


Janet Hanlin

Admin

Weekly Ontario Update for Friday, February 2, 2024:

Unless indicated otherwise, information in this update includes data up until Saturday, January 27, so data is delayed. Data relating to deaths is even further delayed as cause of death is taking MONTHS to be determined. So recent deaths are far worse that are reported.
  • Recent cases: 1,975 (- 362 over 7 days compared to last week)
    🙂

    - Average: 281 new cases per day (- 52 per day since last week)
    🙂

    Estimates suggest that the actual number of new cases could be more than 10 times higher than what is being reported due to limited eligibility for testing!
  • Weekly positivity rate: 12.2% (- 1.7%)
  • Recent deaths: 20 (12 fewer than last week)
    - Average: 3 deaths per day (- 2 deaths per day since last week)

    Recent deaths are a lagging indicator of the current level of new cases. Deaths are underreported because they are based on date of death and by the time the cause of death is reported, it is no longer considered recent!
  • Estimated new hospital admissions (January 14 - 20): 103* (- 10, based on initially reported number last week, see next point)
    - Previous week's new hospital admissions for January 7 - 13 have been updated to: 163 (+ 60)
    *Please interpret the COVID-19 hospitalization data with caution.
    The completeness of COVID-19 hospitalization data, which PHO obtains from the provincial Case and Contact Management database (CCM), has been declining over the course of the 2023-24 surveillance period. PHO is currently working on updates to the ORVT that will include enhancements to respiratory outcome indicators (i.e., hospital bed occupancy), which will help to support surveillance and reporting on COVID-19 outcomes. These updates will be live in the coming weeks.
    .
    The completeness of COVID-19 hospitalization data, which PHO obtains from the provincial Case and Contact Management database (CCM), has been declining over the course of the 2023-24 surveillance period. PHO is currently working on updates to the ORVT that will include enhancements to respiratory outcome indicators (i.e., hospital bed occupancy), which will help to support surveillance and reporting on COVID-19 outcomes. These updates will be live in the coming weeks.
Full list of those eligible for testing can be found here (updated): https://www.ontario.ca/.../covid-19-testing-and-treatment...
Sources: Total cases, total deaths, testing levels and wastewater levels: https://www.publichealthontario.ca/.../Respiratory-Virus...
Some additional COVID stats and info: https://twitter.com/MoriartyLab
 

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COVID variant JN.1 now more than 90% of cases in U.S., CDC estimates​


By Alexander Tin
Edited By Paula Cohen
February 5, 2024 / 11:09 AM EST / CBS News

Close to all new COVID-19 cases in the United States are now being caused by the JN.1 variant, the Centers for Disease Control and Prevention says, with an estimated 93.1% of infections now blamed on the highly mutated strain.

The CDC's latest biweekly estimate of the variant's spread was published Friday. It comes as key trends reflecting COVID-19's spread are now showing signs of slowing, following a peak over the winter holidays.

"Several key indicators are showing decreasing levels of activity nationally," the agency said Friday in its weekly respiratory viruses report.

Only the South has seen trends of the virus rise in wastewater over recent weeks, according to the CDC's tally through Feb. 1.

Most parts of the country are also seeing steep slowdowns in COVID-19 cases diagnosed in emergency rooms, except in the South where trends now appear to have roughly plateaued in some states.

The agency also published new data Thursday from its pharmacy testing program that suggests this season's updated COVID-19 vaccines had 49% effectiveness against symptomatic JN.1 infection, among people between two to four months since they got their shot.

"New data from CDC show that the updated COVID-19 vaccines were effective against COVID-19 during September 2023 – January 2024, including against variants from the XBB lineage, which is included in the updated vaccine, and JN.1, a new variant that has become dominant in recent weeks," the CDC said in a post on Thursday.

CDC officials have said that other data from ongoing studies using medical records also offered "early signals" that JN.1's severity was indeed not worse than previous strains. That is a step beyond the agency's previous statements simply that there was "no evidence" the strain was causing more severe disease.

The CDC's new variant estimates mark the culmination of a swift rise for JN.1, which had still made up less than half of infections in the agency's estimates through late December.

Some of the earliest samples of the strain in the global virus database GISAID date back to August, when cases of JN.1 – a descendant of an earlier worrying variant called BA.2.86 – showed up in Iceland and Luxembourg.

By the end of September, at least 11 cases had been sequenced in the U.S., prompting renewed concern that BA.2.86 had picked up changes that were accelerating its spread around the world.

The World Health Organization stepped up its classification of JN.1 to a standalone "variant of interest" in mid-December, citing the variant's rapid ascent. Health authorities in the U.S. have declined to do the same, continuing to lump the strain in with its BA.2.86 parent.
 

Have you been infected with COVID-19 multiple times? There might be something else going on​

By Mazoe Ford
Posted Yesterday at 2:47pm
Man in white shirt coughing or sneezing into elbow with white background

COVID infections put people more at risk of complications like heart disease and lung disease.(Pexels: Cottonbro Studio)
abc.net.au/news/nsw-multiple-covid-19-infections-health-immunology/103417278

  • In short: Immunology experts say contracting COVID multiple times is a sign there could be a problem with the immune system.
  • Researchers have found the more times you're infected the higher chance you have of developing long COVID or other chronic health conditions.
  • Those at risk are urged to be up to date with their booster vaccinations.
The first time 41-year-old Evan James caught COVID-19 in 2022 he said it "absolutely destroyed" him.
He would go on to be infected another four times.
"Each time has been very different," Mr James told the ABC.
"The first time it wiped me out – three weeks are still a blur, I couldn't get up off the couch, I sweated constantly."
Evan James has had COVID five times.( ABC News: Mazoe Ford )
The Sydney barrister said he was asymptomatic the second and fourth times and had mild symptoms the third time, but by the fifth infection he was "hit very hard again" and was prescribed anti-viral medication.
Mr James was one of dozens of people who responded to an ABC News Sydney call out on social media to hear from people who had been infected with COVID-19 multiple times.
Seventy-six people wrote in with a range of symptoms, severity, and duration.
Most respondents had been reinfected three times, but there were also people who had tested positive four and five times.
One woman reported nine infections.

Why are people getting COVID-19 multiple times?​

Professor Steven Faux, a rehabilitation and pain physician at Sydney's St Vincent's Hospital and co-director of the hospital's long COVID clinic, told the ABC there were two main explanations.
"Getting COVID-19 multiple times means either you're exposed to it a fair bit and you're not as diligent protecting yourself, or there might be something wrong with your ability to fight infections," Professor Faux said.
"It's probably the former, it's probably that people are now becoming lackadaisical about protection and that's not without reason because I think people are fed up, but it's still a serious illness, it's still more serious than flu.
"The fact that it's a highly contagious makes it more of a worry and it keeps mutating, so the vaccines are never absolutely perfect."
Professor Steven Faux said it's likely multiple COVID infections stem from lack of protection.(ABC News: Brendan Esposito)
Professor Stuart Tangye, the head of immunology and immunodeficiency laboratory at the Garvan Institute of Medical Research, said that people who keep getting infected should see a doctor.
"What COVID has shown us is that there are some people who have holes in their immune system," Professor Tangye said.
"If you're susceptible to repeated SARS-CoV-2 infections, maybe you've got an underlying immune problem so get it checked for peace of mind, but also for information."

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A woman lying in bed blowing her nose with a tissue.
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Professor Tangye said he would advise people who had tested positive over and over again to go to GP and get a referral to a clinical immunologist for a blood test to measure immune markers.
Mr James said he is planning to do that.
He is already immunocompromised because of autoimmune disease vitiligo, and because he has had whooping cough several times despite being regularly vaccinated against it.
He wants to find out more about the effect COVID-19 is having on his body.
"Part of [catching COVID-19 five times] is the nature of my work, because at court you're exposed to so many people, you're always a high risk of catching whatever is going around," he said.
"But I'm hoping that I can get an appointment to eventually to see an immunologist."Professor Stuart Tangye said repeated COVID infections could be related to immunity concerns.(Supplied)
Four years since COVID-19 spread around the world, medical researchers are still studying the effects on human health.
"The picture that's starting to come together is clearly the more times you do get infected with SARs-CoV-2, the more you're at risk of ongoing clinical complications [such as] heart disease, lung disease, kidney disease," Professor Tangye said.
"And the more times you get infected, the higher likelihood you're going to have long COVID or chronic health conditions manifesting in time, so it's an ongoing problem."

Who can get a booster shot now?​

Professors Faux and Tangye said people should discuss booster vaccinations with their GPs.
The Australian Government's current advice about booster shots is that they are "recommended" for:
  • All adults aged 65 years and over
  • Those aged 18-64 who have medical comorbidities that increase their risk of severe COVID-19
  • Those aged 18-64 who have a disability with significant or complex health needs
The advice also states that adults without risk factors for severe COVID-19 and children over five with medical comorbidities that increase their risk of severe COVID-19 illness or with a disability or complex health needs, can "consider" a booster dose.
A second booster dose is recommended for all adults aged 75 years and over.
Professor Raina MacIntyre said the mentality to COVID needs to be moved forward to the present day.(ABC News: Brendan Esposito)
Professor Raina MacIntyre, the head of the biosecurity program at the Kirby Institute at the University of NSW, said she thought Australia's vaccine policies were "too restrictive".
"A problem around COVID is that we're still stuck in a 2020 mentality, and in 2020 it was clear that it was older people who were dying and getting hospitalised," she told the ABC.
"That remains true, but we've now got mountains and mountains of data showing that it's a serious infection in any age group.
"We've had so many stories about athletes and healthy young people either dropping dead, or having a cardiac arrest, or developing long COVID and becoming debilitated, so if you don't think you're vulnerable COVID might make you vulnerable."

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Professor Faux said anyone who is not in the "recommended" vaccine booster categories, but still feels at risk because of their job or lifestyle should get a booster.
"Some of the public health people might say, 'if you're fit don't worry about it', but if you're going to be in situations where you have no idea about the risk pool I would recommend regular vaccinations."
"This doesn't stop you from catching it, but it does is it means you're not going to be out of the picture for a long time and won't be admitted to hospital."
Posted Yesterday at 2:47pm
 

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