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Covid Situation Report: Aug 29, 2024​

Update on Covid providing information on prevalence and hospital admissions for England and its regions. This post is best viewed using the browser or Substack app.​


BOB HAWKINS
AUG 29, 2024
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Introduction.

This report is part of a weekly series that summarises the Covid situation in England and its regions.

A reminder that not all of the data previously included in the situation update is now available on a weekly basis. Where relevant, changes to the content and data sources have been noted.

This week's report contains data on weekly Covid hospital admissions from the UKHSA surveillance report, which is now released biweekly. Additionally, it includes case rates from the UKHSA Covid dashboard and the latest available data for Scotland, Wales and Northern Ireland. Finally, there is a summary of a recent report on regional inequalities in Long Covid prevalence.

Summary.

Once again, the latest data for England, Scotland, Wales, and Northern Ireland show a continuing decline in Covid levels, indicating the end of the latest wave.

Over the past week, the test positivity rate in England has continued to fall, signalling that the summer wave is over. Hospital admission rates have also continued to fall.

In addition, case rates in England have continued to fall across all regions.

In Scotland, hospital admissions and the number of beds occupied by Covid patients have also continued to fall and are now well below the summer peak.

Wales has seen a continued and significant decrease in Covid cases and hospital admissions, indicating the end of the recent wave.

Northern Ireland is experiencing a similar trend, with hospital admissions for community-acquired Covid falling from the latest peak although levels have plateaued over the past few weeks.

Although the data indicates that this recent wave is over, this is an important reminder that Covid is not presently a seasonal disease and may never become one. As such, we should anticipate potential future waves with the emergence of new variants and as immunity levels diminish.

With that in mind, the UK Health Security Agency has released the eligibility details for the Autumn 2024 booster campaign, which largely follows the criteria of previous autumn campaigns.

As always, it’s important to remember that the risk of hospitalisation from Covid infection increases significantly with age and for those immunocompromised. Also Long Covid remains a risk for all as shown by the recent ONS report. Therefore, it is prudent to take appropriate measures such as self-isolating when experiencing Covid symptoms and enhancing ventilation or wearing masks whenever possible.

For those who are interested, I recently published an article covering the ONS data on Long Covid in more detail which can be found here. Also a comprehensive review of the evidence in support of wearing masks is available here.


Status of main respiratory diseases in England.

This section starts with the latest available data on positivity rates for primary respiratory infections in England. It is important to understand that positivity differs from prevalence, which refers to the overall percentage of COVID-19 in the general population. Appendix 1 provides a more detailed explanation of the difference and why positivity rates are a useful indicator of trends in Covid infection levels.

The chart below displays the test positivity rates for the main respiratory illnesses in England, including Flu, Covid, RSV, and Rhinovirus.


Over the past two weeks, the Covid positivity rate has fallen to 6.7% for week ending Aug 25 indicating that Covid levels in the general population are falling. Meanwhile, the flu positivity rate remains significantly lower than that of Covid. Additionally, RSV rates have dropped to very low levels, accompanied by a fall in Rhinovirus rates.

The next chart shows the trend for Covid positivity rate by age. Hover your cursor over one of the chart lines to display the positivity rate for all ages. For comparison the grey line shows the positivity rate for all age groups.


The test positivity rate has continued to fall across all age groups except for those between 15 to 44 years old which saw a slight increase in the past week. Positivity rates continue to be highest among those aged 65 and older, but it's important to note that most tests are currently performed on hospital patients, who tend to be older as they are more susceptible to hospitalisation due to Covid.

The final chart in this section shows weekly hospital admissions per 100,000 people in England for the main respiratory diseases.


Consistent with the test positivity rate data, the past two weeks have seen weekly hospital admission rates for Covid fall indicating that the summer wave of infections is over. Note that hospital admission data for Flu and RSV is no longer published.

Although age-specific data for hospital admissions are no longer released, earlier statistics on Covid hospital admissions and the current test positivity rates by age indicate that the rise in hospitalizations will primarily impact the over 65 year olds.

It's important to note that while testing policies have been updated from April 1, 2024, the guidelines for testing patients showing Covid symptoms or when a positive result would change the patient's treatment remained unchanged. Consequently, the number of Covid hospital admissions should be a dependable indicator of the virus's prevalence in the community for the period shown in these charts.


Covid case rates in England​

The UKHSA Covid dashboard continues to publish daily case rates for England on a weekly basis. As the majority of testing now occurs in hospitals or under medical supervision, these rates should closely align with hospital admissions. However, a comparison of daily case rates and daily admissions shows that this is not the case.

Appendix 1 indicates that although Covid case rates typically reflect the pattern of hospital admissions, there is a notable discrepancy in the magnitude of changes, with admissions experiencing a more pronounced fluctuation than case rates. Therefore, while case rates are helpful in signalling the general trend of Covid within the population, they do not precisely represent the degree of change.

The first chart in this section shows daily case rate per 100,000 individuals.


The chart indicates that Covid case rates have peaked and fallen for the past seven weeks indicating that the ‘summer’ wave is over. Current case rates are now lowers than those observed during the peak in May. It is important to note, as detailed above and in Appendix 1, that comparisons with the peak in Winter 2023 are not recommended.

The next panel chart in this section shows Covid rates for the regions of England. Hover your cursor over one of the chart lines to display the admission rates for all regions.


The panel charts indicate a consistent decrease in daily case rates across all regions. The North East region, once the area with the highest Covid rate, has seen a substantial drop and is now surpassed by the East Midlands.


Daily Covid hospital admissions and bed occupancy.​

This section gives a more detailed examination of the most recent daily Covid data for hospitals in England.

NHS England stopped the weekly publication of data used to create these dashboards from April 4, 2024 and have moved to a monthly publication schedule. The next update will be on September 12, 2024 covering August Covid hospital admissions and bed occupancy.

Scotland weekly hospital admissions and bed occupancy​

Scotland continues to publish weekly data on hospital admissions and bed occupancy for Covid as well as waste water monitoring data. The dashboard for Scotland’s data can be accessed here.

The following panel chart shows the most recent data for weekly Covid hospital admissions up to Aug 18, depicted in blue, together with the number of beds occupied by Covid patients up to Aug 25, shown in orange. The number of occupied beds represent patients being treated for Covid as well as those being treated with Covid.


The charts shows that the recent 'summer' Covid wave in Scotland has led to more hospital admissions and a greater number of beds occupied by Covid patients compared to the 'winter' wave. This contrasts with England, where 'summer' hospital admissions did not surpass those seen in 'winter'.

However, in the past seven weeks Covid admissions and bed occupancy in Scotland have fallen quite quickly and this ‘summer’ wave is over.

Finally, although Scotland remains the only home nation that is monitoring Covid levels using wastewater sampling, there was no update to the data provided this week.


Wales Covid cases and hospital admissions.​

Public Health Wales publishes a weekly Covid dashboard, presenting key Covid hospital indicators for the preceding 90 days. This dashboard can be found here. Additionally, data regarding Covid cases detected through testing in hospitals and other medical facilities are released every week.

The following chart presents the latest data for the weekly number of cases reported.


The chart shows a significant decline in Covid cases in Wales over the past week, with numbers now approaching low levels. This decrease comes after a spike in cases that exceeded the 'winter' wave, culminating in the highest peak in more than a year.

The following chart gives the trend for weekly hospital admissions in Wales.


Hospital admissions for Covid increased in June, but have now fallen significantly for the past seven weeks, mirroring the trend observed in Covid cases, and confirming that the ‘summer’ wave is over.


Northern Ireland hospital admissions​

Public Health Northern Ireland publishes a weekly COVID-19 Epidemiological Bulletin that provides data on Covid cases, hospital admissions and occupancy and care home incidents. The full report, published every Thursday, can be found here.

The chart below presents the weekly count of Covid hospital admissions for cases where the infection was contracted in the community, thereby excluding patients who contracted Covid while in hospital. It is important to note that the hospital admissions data for other home nations include patients who contracted infections in the hospital, making them not directly comparable to the data from Northern Ireland.



The chart shows a similar pattern to that seen in Scotland Wales, with the 'summer' wave's peak nearly reaching the heights of the 'winter' wave. However, since then the number of admissions has fallen and has now stabilised indicating that this 'summer' wave over.


Regional inequalities in Long Covid prevalence.​

Last week, Health Equality North published a report called Navigating the Long Haul: Understanding Long Covid in Northern England. The report examines regional differences in rates of Long Covid, the relationship with socioeconomic deprivation, the impact of the illness on sufferers lives and how employers manage the condition. It uses data from the 2022 annual General Practice Patient Survey (GPPS) of just over two million patients registered at each general practice in England. In addition, patient interviews were carried out to capture the lived experience of Long Covid sufferers. The report can be accessed here.

Analysis of the GPPS showed that national prevalence of people reporting having symptoms of Long Covid for more than 12 weeks in 2022 in England was 4.4%. The following chart shows the self-reported Long Covid prevalence by region.


The chart indicates significant regional disparities in prevalence. The highest rates were observed in the North West at 5.5% and the North East and Yorkshire at 5.1%. Conversely, the lowest rates were recorded in the South West at 3.4% and the South East at 3.6%.

Significantly, the ten general practices reporting the highest rates of Long Covid were all located in the Northern regions. In the North East and Yorkshire, as well as the North West, there were some practices where at least 20% of patients were affected by Long Covid.

Further analysis of the GPPS survey found significant inequalities in Long Covid prevalence based on deprivation as shown in the following chart.


The chart indicates that in England, the prevalence rate in the most deprived decile is 6.3%, which is almost double the rate in the least deprived decile at 3.3%. The report highlighted significant evidence of socioeconomic disparities in Long Covid prevalence within the North East and Yorkshire. Specifically, the incidence in the most deprived group was 8.3%, which is 5.2 percentage points greater than the 3.1% observed in the least deprived areas.

In addition to the quantitative data, Health Equality North carried out a series of interviews and workshops to explore people’s experiences of living with Long Covid in North East England. The report indicated that Long Covid includes a range of physical, cognitive, and psychological impairments, with the most frequently reported symptoms being brain fog, fatigue, breathlessness, low mood, and depression.

The severe impact of these symptoms significantly hampered participants’ lives, impeding their capacity to work and carry out routine activities. In particular, Long Covid sufferers experienced a degree of social isolation, which was exacerbated by a lack of effective communication with non-ill individuals. Long Covid also had a significant impact on working life and employment prospects. Many participants had been demoted, fired, forced to resign or switch to part-time work because of Long Covid.

The report closes with a recommendation for Government to:

  • Develop programmes for employers to support members of their workforce with Long Covid, and
  • Consult with Long Covid patients to better understand their condition and to implement care plans to facilitate their rehabilitation and improve management of the condition.

In conclusion​

Although the amount of data currently being published has decreased, the information available for England show that Covid levels are now falling and the summer wave is over.

Data from Scotland, Wales, and Northern Ireland indicate that the recent 'summer' wave of Covid saw higher levels than the 'winter' wave. Nevertheless, the latest figures show that Covid levels are continuing to fall and this recent surge has ended.

As always, if you have any comments on this Covid Situation Report or suggestions for topics to cover, please post a message below.


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Appendix 1. Test positivity rates and prevalence

Positivity rates are derived from the results of hospital laboratory tests conducted on patients exhibiting symptoms of respiratory diseases. Test positivity is the percentage of patients who test positive for Covid of the total number of patients tested. Since the individuals tested for this measure are not a representative sample of the general population it differs from prevalence, which is derived from a representative sample of the population.

Test positivity rates, while not directly estimating the number of Covid infections in the general population, can be a valuable indicator of the infection trend. The panel chart below compares the weekly test positivity rate among hospital patients with respiratory symptoms to the prevalence of Covid in the general population, as reported in the Winter Infection Survey.


The chart shows that the weekly test positivity rates for patients with symptoms of respiratory infections follows the same pattern as the prevalence for Covid reported by the Winter Infection Survey. Since the Winter Infection Survey is based on a representative sample of the general population this supports using test positivity as a useful proxy for infection trends.


Appendix 2. How reliable are Daily Covid Case Rates?

The UKHSA Covid dashboard continues to publish daily case rates for England on a weekly basis. As the majority of testing now occurs in hospitals or under medical supervision, these rates should be closely aligned with hospital admissions and the positivity rate of tests.

The first panel chart in this section tests that assumption by comparing the daily case rate per 100,000 individuals, shown in red, with daily hospital admissions for Covid reported by NHS England, depicted in blue.


The chart shows that while Covid case rates generally mirror the pattern of Covid hospital admissions, there is a significant disparity in the scale of changes. The grey shaded areas on each chart highlights the difference between the peak of the winter wave and the recent peak in June. Case rates experienced a 64% decrease, whereas hospital admissions saw a reduction of only 32% between the winter and June peaks.

In conclusion, although case rates are useful for indicating the overall trend of Covid in the population, they do not accurately reflect the extent of change. The likely reason for this is that testing levels have decreased by about a half since January.
 

COVID-19 levels rising in N.S. this summer, but same precautions apply, says province​

746 new cases, 21 long-term care outbreaks reported from July 21 to Aug. 24​

CBC News · Posted: Aug 30, 2024 5:35 PM EDT | Last Updated: 2 hours ago
A woman with long black hear who is wearing a mask holds a syringe.

COVID-19 cases in Nova Scotia have spiked over the past month, according to the latest Respiratory Watch numbers. (Ben Nelms/CBC)

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The number of COVID cases in Nova Scotia has more than doubled over the past month, according to the province's latest COVID-19 update.

In the Respiratory Watch covering the period from July 21 to Aug. 24, the province reported 746 new cases of COVID-19. That's up significantly from the 362 cases reported between June 24 and July 20.

There were 21 outbreaks at long-term care facilities in the most recent period, up 300 per cent from the previous report, when there were only seven. According to the province, an outbreak is declared at any place with two or more connected cases.

In the 2023-24 reporting period from Aug. 27, 2023, to Aug. 24, 2024, there were 969 total non-ICU hospitalizations due to the virus, up from the 900 documented in the last reporting period. ICU admissions were up slightly to 104, from 98 in the previous period.

Four more people, meanwhile, were reported to have died from COVID-19 since the last monthly update, bringing the total number of deaths for the 2023-24 reporting period to 245.

'This is how we live with COVID-19 now'​

Overall, the numbers represent higher levels of COVID-19 than in the spring, but Jennifer Cram, the province's regional medical officer of health for the western zone, said they're not entirely unexpected.

"This is how we live with COVID-19 now," Cram said in an interview with Information Morning Nova Scotia earlier this week, before the latest numbers were made available.

"We are going to see circulation likely 12 months of the year, more at different times."

Cram said that unlike other respiratory illnesses like influenza, which is at its peak in the fall and winter, there is no distinct period when COVID-19 is especially prevalent.

Instead, she said, it "ebbs and flows" but one silver lining is that the virus has evolved to become less damaging over time, even though it can still have serious complications, especially for those in high-risk groups.

"This is a virus that's shown us that over and over and over again it's going to continue to evolve, but fortunately, it doesn't seem to be getting more severe and that's good news," Cram said.

As back-to-school season begins, she said it will be important for people to use common sense by staying at home or keeping their child home if they're sick, masking if not feeling well, and making sure to get the latest vaccinations as they become available.

It's just as important, she said, for children to receive the latest vaccines for influenza and for whooping cough, which has recently been on the rise in some areas of Canada, though at this point not in Nova Scotia.

"We really need to take all of these different infectious respiratory illnesses seriously," said Cram.

In an emailed statement Friday, the province's Department of Health and Wellness said new vaccines for COVID-19 and influenza will be available in October.

"There has been an increase in COVID-19 cases and hospitalizations compared to the spring, however, levels remain lower than they were … during the peak of respiratory season in Fall 2023," said the department.
 

An even more contagious COVID strain is ‘just getting started’ amid California wave​

A pharmacist bends over, preparing vaccines for a man standing behind him.

Pharmacist Deep Patel, left, prepares flu and COVID-19 vaccines for Brandon Guerrero, 34, of Compton, at CVS in Huntington Park on Wednesday.

(Christina House / Los Angeles Times)
By Rong-Gong Lin IIStaff Writer
Aug. 30, 2024 Updated 12:45 PM PT
The summer surge of the coronavirus subvariants nicknamed FLiRT has given way to ever more contagious strains, a key reason behind the current high levels of COVID in California and nationwide.

And doctors and scientists are keeping an eye on yet another subvariant — XEC — that could surpass the latest hyperinfectious subvariant, KP.3.1.1, now thought to be the most common nationwide. XEC was first detected in Germany and has since seized the attention of doctors and scientists worldwide.

XEC “is just getting started now around the world and here,” said Dr. Eric Topol, director of the Scripps Research Translational Institute in La Jolla. “And that’s going to take many weeks, a couple months, before it really takes hold and starts to cause a wave.˜

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“XEC is definitely taking charge. ... That does appear to be the next variant,” Topol added. “But it’s months off from getting into high levels.”

While XEC has shown up in the United States, its prevalence is low and it is not being individually tracked on the U.S. Centers for Disease Control and Prevention’s variant tracker website. A lineage must be estimated to circulate above 1% nationally over a two-week period for it to be tracked.

Los Angeles, CA - July 07: A large number of travelers make their way through Tom Bradley International Terminal at LAX, as a record amount of passengers pass through the airport today wrapping up a busy July 4th holiday on Sunday, July 7, 2024 in Los Angeles, CA. (Jason Armond / Los Angeles Times)
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The expected midyear wave began in May, when the winter’s dominant subvariant, JN.1, gave way to a number of subvariants nicknamed FLiRT — a cheeky name based on the letters of two key mutations, F456L and R346T, Topol said. (Focus only on the letters and add an “i” as a connector, and you get FLiRT, which includes the officially named KP.2 subvariant.)

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Then, “the FLiRT eventually gave way to new variants that had even more growth advantage,” Topol said.

A successor subvariant, KP.3, had a different mutation — Q493E — and dropped R346T. It was nicknamed FLuQE, pronounced “fluke.” And an even more contagious subvariant — KP.3.1.1 — had a mutation that was deleted, giving it the unofficial moniker deFLuQE, or “de-fluke.”

The “S31 deletion,” Topol said, is “what’s made that a kind of very pathogenic, very immune evasive variant. That S31 deletion has been studied — particularly by the Sato lab in Japan — and that’s the culprit that’s making this wave prolonged and getting into a lot of people who otherwise might have ... not gotten sick.”

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“The KP.3.1.1 is definitely an outlier for growth advantage,” he added. “It’s not over yet, obviously. And we’re going to have new variants beyond KP.3.1.1.”

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KP.3.1.1 is still estimated to be the nation’s most common subvariant. For the two-week period that began Aug. 18, KP.3.1.1 was estimated to make up 42.2% of coronavirus samples nationwide, up from 19.8% a month ago, according to the CDC.

The Moderna and Pfizer vaccines that just came out just before the Labor Day weekend are designed against KP.2, a predecessor of KP.3.1.1, so they are a relatively close match for the main circulating variants. XEC, however, won’t be as closely aligned.

The new vaccines are still way better for the current season compared to the shot released a year ago, which targeted XBB.1.5, but the difference between what the latest vaccine is designed against and XEC, is “pretty substantial ... and we’ll see how it plays out,” Topol said.

“It would be surprising if this doesn’t turn out to be the next challenge,” Topol said. Still, “any booster will help induce a higher level of immunity.”

Dr. Elizabeth Hudson, regional chief of infectious diseases for Kaiser Permanente Southern California, said she thought the new vaccines would still provide some good protection against XEC “because there is some overlap, because these are all sub, sub, sub-grandchildren of the original Omicron. So there is still going to be some level of protection there.”

“We’re not like in a new Greek letter — they’re not that much different; it’s not like something completely new,” Hudson said.

XEC is a recombination of two different, little-discussed subvariants: KS.1.1 and KP.3.3, Hudson said. “It’s definitely one that I have my eye on,” she said.

“But this is a little bit different, and it does seem to be showing what we call a growth advantage over the JN.1, or the deFLuQE variants, or the FLiRT variants,” Hudson said.

“It’s going to be a little hard to know where this is going to go, because right now, KP.3.1.1 really still is the predominant variant,” Hudson said. “So we have to really monitor not only what’s happening within the U.S., but also what’s happening in Europe as they get more towards their colder seasons.”

HUNTINGTON PARK-CA-AUGUST 28, 2024: Cynthia Blancas, 42, of Lynwood, receives a Covid-19 vaccine by pharmacist Deep Patel, right, at CVS in Huntington Park on August 28, 2024. (Christina House / Los Angeles Times)
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Besides Germany, XEC has been reported elsewhere in western Europe, including the Netherlands, and has spread relatively quickly, Hudson said.

“We’ll really have to watch — because the overall info on it is not super robust now — but I would imagine over the next couple of weeks, particularly if it starts to creep up higher and higher, we will be hearing a little bit more about it,” Hudson said.

COVID has proved to be far more wily than the flu. Instead of one fall-and-winter wave, as flu typically delivers, COVID seems to bring two waves each year.

There are several reasons for that difference. “One is that the virus keeps evolving, and it takes that long for a variant to really pick up steam and to become dominant,” Topol said.

The second is that our immunity — at least in terms of infection — is short-lived, allowing many who recover in the winter to get COVID again in the summer, Topol said. (Luckily, protection against hospitalization and death has been more durable, explaining why hospitals are no longer strained despite high levels of coronavirus circulating nationwide.)

And finally, few people are adhering to precautionary measures that were far more common years ago, Topol said. Fewer people are wearing masks in crowded indoor settings, staying up to date on their vaccinations or even staying home when sick.

As of spring, 22.5% of U.S. adults and 29.1% of a subset of seniors 65 and older got the COVID-19 vaccination for the 2023–24 season. Vaccination rates were higher for the flu, estimated to cover 48.5% of adults and 50.6% of seniors.

In California as of July 31, 37% of seniors had received the updated COVID-19 vaccine for the 2023–24 season, as did 18.7% of those age 50 to 64, and 10.1% of the youngest adults.
 

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Covid cases on the rise​


 

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