Iran should retaliate against Israel's Dimona reactor. Regime change in Iran is impossible unless if they can kill all of 500,000 IRGC members and over 10 million Basiji militia.
Islamic Republic will live on unless if the Evil West dares to destroy the entire Iranian Nation with 100 Nukes which they simply won't do for fear of being Nuked by China or Russia(because nothing stops USA from Nuking them if they can do it without Repercussions against a Sovereign Country that didn't started the war in the first place).