I doubt any Syrian, whether secular or Jihadi, would let Israel rest in peace in the newly occupied land--which is supposed to be already three times the size of Gaza! But 'facts on the ground' are facts which can't be ignored. Israel is within a very short drive to Damascus now and also occupies the high peaks to overlook Lebanon and Syria. Already, per a report, one of five supply vehicle from Iran to Lebanon was successfully destroyed, so the new Israeli deployments would make the supplies much harder. And let's not bring in air or sea routes: Israel had targeted sea supplies to Lebanon/Syria before and would make air supplies impossible by destroying the Beirut Airport if need be. The Houthis in Yemen were supplied because they were not perceived a large threat to Israel--the Houthis may have served well the purpose of keeping Muslims fighting each other while the arms industry in America made untold billions from that conflict. But now the Houthis are a big target.
Having said all this... I don't see Israel finding peace despite its gains in Syria. Once a Jihadi, always a Jihadi. The CIA money may buy the leaders but the cadre of the Syrian resistance will turn against Israel before long. Bottomline: Israel will NOT find peace until it gives peace to the regional entities.