In my opinion, Iran has fought one major conventional interstate war over the past 47 years, whereas the United States has been involved in numerous military operations and conflicts during the same period.
Many countries also send military officers to train in the United States or participate in US-led military education and exchange programmes. In my opinion, that breadth of operational experience and training gives the US military significant advantages in many areas.
If US and Iranian forces were ever to engage directly, I believe American personnel would likely benefit from their broader combat experience, training, and institutional expertise.