Maldives sacks multiple ministers to pacify India

AstraZeneca does not agree. They say their producer cells are derived from cells first created more than 50 years back (and they are saying this since 2020). So.... I guess it kind of tells us that they are different.

Besides, even in HEK293, there are variants in cell lines and yes viruses can grow in multiple variants.

My belief is that for patent purposes, AZ has some kind of variant of original cells behind HEK 293 that they created in a proprietary fashion in-house. Which will explain how they can claim more than 50 years of past.

It is very common in pharma to create cells or molecules that are functionally identical but structurally different to avoid patent entanglement or to patent. As you know both processes and products can be patented, so yes, it could be a deliberate attempt to protect IPR of production or to avoid falling in a IPR trap.

So yes, it is very much possible that while SII is indeed a generic manufacturer of vaccines that grow in HEK 293 line, AZ have their own proprietary culture and process compatible with HEK-293 that is used in research and manufacturing.
Just go through the product insert for AstraZeneca covid 19 vaccine that I had attached in my previous post. You'll find that it uses same cell line.

AstraZeneca does not have any need to get patent for the cell lines. It is just a culture media to replicate the viruses. No added benefit to go through the trouble of tweaking them unless necessary for the growth of the said vaccine virus.
 
Just go through the product insert for AstraZeneca covid 19 vaccine that I had attached in my previous post. You'll find that it uses same cell line.

AstraZeneca does not have any need to get patent for the cell lines. It is just a culture media to replicate the viruses. No added benefit to go through the trouble of tweaking them unless necessary for the growth of the said vaccine virus.

Dosent it sounds familiar :

1704780228559.png
 
Just go through the product insert for AstraZeneca covid 19 vaccine that I had attached in my previous post. You'll find that it uses same cell line.

AstraZeneca does not have any need to get patent for the cell lines. It is just a culture media to replicate the viruses. No added benefit to go through the trouble of tweaking them unless necessary for the growth of the said vaccine virus.
The leaflet says "genetically modified human embryonic kidney (HEK) 293 cells"...

This is NOT a very specific description of a specific cell line. HEK 293 has MANY variants. Is it HEK 293F (https://www.thermofisher.com/order/catalog/product/R79007) or HEK 293FT (https://www.thermofisher.com/order/catalog/product/R70007) or HEK 293T or some proprietary variant is completely unknown.
 
Seniority and experience is always to be respected, sir. But it is also one's duty to correct when somebody is wrong.

I also have a genuine free advice for you sir.

Limit your screen time. I'm concerned by your 24X7 presence on this forum. Digital well-being is very important.


I do hope you consider this advice.
Of course! That will reduce the number of irrelevant posts that I have to read before deciding they deserve no further attention. Good advice.
 
Hey can we move this discussion to Vaccine thread and discuss on Lakshadweep.
 
Also can we please thread unban @Guynextdoor

@Waz @Mr X @RescueRanger @Musings

The poor chap started the thread. And has been locked out since Day 1.

Reading in. Unable to contribute. And the thread is on Page 32 now. One of the highest trafficked on the forum.

Cheers, Doc
 
That is why some basic education is called for.
The country was NOT divided on the basis of religion.
Get your fundamentals clear.
Focus on Maldives and Laccadives.


* Maldives opposition parties have called for No Confidence Motion against ruling government.

* Indian travel insurance company , InsuranceDekho' has suspended it's operations for Maldives.

* Maldives president has formally requested for India visit this month to normalize ties.

* Superstar Amitabh Bachchan has joined the #SupportLakshadweep campaign.
 
Focus on Maldives and Laccadives.


* Maldives opposition parties have called for No Confidence Motion against ruling government.

* Indian travel insurance company , InsuranceDekho' has suspended it's operations for Maldives.

* Maldives president has formally requested for India visit this month to normalize ties.

* Superstar Amitabh Bachchan has joined the #SupportLakshadweep campaign.
A single tweet from a single individual (a RW troll no less) created such a massive shit storm?

I am wavering in deciding if this is organic or someone put it in place like this. Hard to imagine, it has too many moving parts...
 
A single tweet from a single individual (a RW troll no less) created such a massive shit storm?

I am wavering in deciding if this is organic or someone put it in place like this. Hard to imagine, it has too many moving parts...

Organic, in my opinion.

Even I feel bad for the old man.

Imagine.

Cheers, Doc
 
A single tweet from a single individual (a RW troll no less) created such a massive shit storm?

I am wavering in deciding if this is organic or someone put it in place like this. Hard to imagine, it has too many moving parts...
Would you like to share my ice-pack?
 
Would you like to share my ice-pack?
My wife gave me her Tiger Balm.... Apparently high intensity dancing can be painful if surface is not as forgiving.

1704783199392.png

I do not know if it works on headache or not... but smell is intoxicating... For the heck of it I just apply it a little bit on near forehead... Smells and sensation is very calming.
 
Organic, in my opinion.

Even I feel bad for the old man.

Imagine.

Cheers, Doc
Heh! I guess one of these days we will see a nuclear war started from twitter. Single most dangerous invention.
 

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