Covid-19 News and Discussions


Weekly case numbers from around Australia: 3,947 new cases (🔻17%), 633 hospitalised, 9 in ICU​

Australia: Case Update

  • NSW 1,332 new cases (🔻17% §); 262 hospitalised
  • VIC 226 new cases (🔻64%); 144 hospitalised; 6 in ICU
  • QLD 888 new cases (🔺3%); 174 hospitalised
  • WA 178 new cases (🔻18%); 15 hospitalised; 1 in ICU
  • SA 876 new cases (🔻12% §)
  • TAS 369 new cases (🔻4%); 23 hospitalised; 1 in ICU
  • ACT 47 new cases (🔺12%); 15 hospitalised; 1 in ICU
  • NT 31 new cases (🔻16%); 0 hospitalised
§ I have applied the same adjustments as last week to calculate the case percentage changes for NSW, SA and Australia. Without those adjustments, we would have had NSW 🔻51% and SA🔺159%, with 🔻24% nationally.
Notes:
  • Older more detailed surveillance reports can be accessed using the state and territory links above.
  • These case numbers are only an indicator for the current trends as most cases are unreported.
  • Multiply by 20 or 30 to get a better indication of actual community case numbers.
  • NSW, VIC, QLD, WA and the ACT no longer collect or report RAT results.
Data is sourced from CovidLive that pulls data from the NNDSS Dashboard for case numbers (updated daily) and the National Dashboard for hospitalisations (updated monthly).
Flu tracker tracks cold and flu symptoms (fever plus cough) and is another useful tool for tracking the level of respiratory viruses in the community.
WA hospitalisations are showing the same slow decrease of admissions as the other states.
r/CoronavirusDownunder - Weekly case numbers from around Australia: 3,947 new cases (🔻17%), 633 hospitalised, 9 in ICU
 

Last updated 2pm 1 April 2024.
This data is updated weekly. All data on this page relates to cases recorded prior to 11:59 pm 31 March 2024.

COVID-19 cases summary​

New case average* RATs uploaded average*
485 ↓ 565 ↓
Cases in hospital as at midnight SundayCases in ICU as at midnight Sunday
168 **
Deaths attributed to COVID*Total deaths attributed COVID
1 ↓ 3,923
* 7 day rolling average
** Not currently available

Current situation​

Summary
In the last weekNew cases reported3399
Reinfections2068
Reinfections (< 90 days)22
Total since first New Zealand caseCases reported2621111
Reinfections354706
Reinfections (< 90 days)26257

Case outcomes since first New Zealand case

COVID-19 casesChange in the last weekTotal
Recovered40362613791
Deceased*73923*
*The Ministry of Health has recently switched its definition of 'deceased' from deaths within 28 days of testing positive for COVID-19 to deaths attributed to COVID-19. See the definitions section below for further details.

Deaths with COVID-19​

Cause of deathDied within 28 days of positive testDied more than 28 days after positive testTotalChange in the last week
COVID as underlying234112124625
COVID as contributory135710414612
COVID-attributed total369822539237
Not COVID17730*17738
Not available2260226-1
Total5697225592214*
*The change in total deaths with COVID may not be equal to the number of new deaths reported today. This is because deaths that occurred more than 28 days after a positive test that are subsequently determined to be unrelated to COVID are removed from the total.
Of the 14 people whose deaths we are reporting today: one was from Northland, six were from Auckland region, three were from Canterbury, one was from West Coast, three were from Southern.
One was in their 60s, four were in their 70s, seven were in their 80s and two were aged over 90. Of these people, eight were women and six were men.

Case details​

Number of active cases
Change in the last weekTotal since first NZ case
Confirmed31852577157
Probable21443954
Total3399*2621111
*The change in total case numbers may not be equal to the number of new cases reported today due to data updating and reconciliation.

Definitions​

Active case - confirmedConfirmed cases are people who have received a positive PCR test OR someone who has received a positive result on a Rapid Antigen Test. For more details, see the COVID-19 case definition.
Active case - probableA probable case is when someone is diagnosed based on their exposure to other people with COVID-19 and on their symptoms.
ReinfectionsReinfections are cases in an individual who reported a case 29 or more days previously.
RecoveredRecovered cases are people who had the virus, where at least 7 days have passed since their symptoms started and they have not had symptoms for 72 hours, and they have been cleared by the health professional responsible for their monitoring.
DeceasedIncludes all deaths where COVID-19 is determined to have been the underlying cause of death or a contributory cause of death.

Cases reported each day​

Daily confirmed and probable cases​

New COVID-19 cases reported each day

This graph shows the count of all cases of COVID-19 every day (all cases – confirmed and probable) since the first New Zealand case in late February 2020. The graph shows the rapid increase of daily cases from mid-February 2022 to early March 2022, driven by the Omicron variant. From mid-March to mid-April 2022, cases rapidly declined, followed by a period of slower decline until early July. This was followed by a rapid increase in cases, peaking in August before a steady decline in new daily cases. Reported new daily cases hit their lowest since February 2022 in September 2022.
New COVID-19 cases reported each day
This graph shows the count of all cases of COVID-19 every day (all cases – confirmed and probable) since the first New Zealand case in late February 2020. The graph shows the rapid increase of daily cases from mid-February 2022 to early March 2022, driven by the Omicron variant. From mid-March to mid-April 2022, cases rapidly declined, followed by a period of slower decline until early July. This was followed by a rapid increase in cases, peaking in August before a steady decline in new daily cases. Reported new daily cases hit their lowest since February 2022 in September 2022.

COVID-19 by location​

Total cases by location​

Total COVID-19 cases by location graph

This bar graph shows the total cases and their status by health district and those with recent travel history.
The ‘At the border’ data group includes cases detected in managed isolation or quarantine facilities from the period when these were operating, as well as cases with recent travel history from after that time. They are not included in the district totals. Before 17 June, people in managed isolation or quarantine facilities were included in the total of the relevant district.
Total COVID-19 cases by location graph
This graph shows:
  • This bar graph shows the total cases and their status by health district and those with recent travel history.
    The ‘At the border’ data group includes cases detected in managed isolation or quarantine facilities from the period when these were operating, as well as cases with recent travel history from after that time. They are not included in the district totals. Before 17 June, people in managed isolation or quarantine facilities were included in the total of the relevant district.

Total cases by location​

LocationActiveRecoveredDeceasedTotalNew cases in the last week
Auckland280246230264246774280
Bay of Plenty114115010183115307114
Canterbury525346065547347137525
Capital and Coast306185357173185836305
Counties Manukau242292921317293480241
Hawke's Bay91860711678632992
Hutt Valley137906559890890137
Lakes61513421115151461
Mid Central1849648620696876183
Nelson Marlborough1377956215679855136
Northland92811011438133693
South Canterbury4934698443479149
Southern306192232372192910307
Tairāwhiti3326620442669733
Taranaki82657231286593382
Unknown62264922797
Waikato290208408389209087291
Wairarapa4225574642568042
Waitematā330309899403310632331
West Coast3415802211585734
Whanganui5634479783461356
At the Border*027292627298NA
Total33972613791392326211113399
* Due to retiring the COVID-19 Protection Framework on 12 September 2022, the Ministry of Health no longer separately reports COVID-19 cases who have recently travelled overseas. These cases will be included in the weekly reporting on all COVID-19 community cases, but we will no longer distinguish between border and other cases.
You can also view a detailed breakdown of daily case numbers for each district since the beginning of the pandemic by clicking the ‘download’ button on the right hand side of this page: New Zealand COVID-19 data.

Note: we cannot give detailed information about cases in your district, city or town, as we must protect the privacy of the people concerned.
 

Friday 05 Apr 2024 @ 10:10
UK Health Security Agency

Flu and COVID-19 surveillance report published​


Weekly national influenza and COVID-19 report, COVID-19 activity, seasonal flu and other seasonal respiratory illnesses.
This COVID-19 and flu surveillance bulletin brings together the latest surveillance data, along with the latest public health advice for COVID-19 and flu.
The flu and COVID-19 surveillance report has been published here.
COVID-19 surveillance data for week 13
COVID-19 activity decreased across most indicators.
SARS-CoV-2 positivity increased slightly to 3.5% compared with 3.1% in the previous week. This is based on a percentage of people who test positive among those with symptoms tested at sentinel “spotter” laboratories, reported through the Respiratory DataMart surveillance system.
COVID-19 case rates and positivity in Pillar 1 decreased overall, within most ethnic groups, and within some age groups and regions in week 13.
COVID-19 hospitalisations decreased slightly to 1.65 per 100,000 compared with 1.75 per 100,000 in the previous week.
COVID-19 ICU admissions remained low and fluctuated at low levels at 0.06 per 100,000 in week 13.
The total number of confirmed COVID-19 acute respiratory incidents decreased compared to the previous week, with 8 incidents reported in England during week 13.
The highest hospital admission rate regionally is currently in the North West at 2.54 per 100,000.
Those aged 85 years and over had the highest hospital admission rate, which decreased to 18.59 per 100,000. A small increase was detected in those aged between 75 and 84 years, whilst small decreases or stabilisation occurred in the remaining age groups.
Details for the Spring 2024 COVID-19 vaccination programme have been confirmed by NHS England. Visits to older adult care homes and eligible housebound patients should begin 15 April 2024. For all other eligible cohorts, vaccinations should start by 22 April 2024 and end on 30 June 2024.
Flu surveillance data for week 13
Overall, Influenza activity decreased.
Influenza positivity decreased to 3.6% in week 13 compared with 4.5% in the previous week. This is based on a percentage of people who test positive among those with symptoms tested at sentinel “spotter” laboratories, reported through the
The total number of confirmed influenza acute respiratory incidents remained stable compared to the previous week, with 12 incidents reported in England during week 13.
Overall, influenza hospitalisations decreased to 1.46 per 100,000 compared with 1.71 per 100,000 in the previous week and crossed the baseline threshold (less than 1.57 per 100,000).
Influenza ICU admissions remained low at 0.03 per 100,000 in week 13.
Emergency department (ED) attendances for influenza-like-illness (ILI) remained stable.
Dr Mary Ramsay, Director of Public Health Programmes at UKHSA, said
We are always pleased to see decreases in flu and COVID-19 activity. However, these viruses are still circulating and causing serious illness and hospitalisations.
If you are showing symptoms of flu and COVID-19, try to stay at home to protect others, especially those who are vulnerable. If you need to go out while you are feeling unwell, consider wearing a mask when around people.
Simple steps like catching coughs and sneezes with a tissue, and regular handwashing can reduce the risk of spreading viruses. Improving fresh air circulation by opening a window whilst meeting indoors can also help minimise the spread.
 

3 min read
Published 6 April 2024 3:00pm
By Ewa Staszewska
Source: SBS News

This country claims to have not recorded any COVID-19 cases​

Despite its neighbours having recorded millions of COVID-19 cases, this country claims it's yet to see one.​

City buildings with mountains in the background.

Ashgabat, the capital of Turkmenistan. Source: Getty / Xinhua News Agency

Key Points​

  • The World Health Organisation has confirmed one country in the world reports being COVID-19 free.
  • It's central Asian neighbours have recorded millions of cases.
  • Previously, the other country claiming to be COVID-free was North Korea.
One country maintains that it has not recorded a single COVID-19 case four years into the pandemic.

There have been at least 775 million infections worldwide, according to the World Health Organization (WHO). But none, apparently, in Turkmenistan — a landlocked nation in Central Asia that borders, among other countries, Afghanistan and Iran.

That, however, is almost certainly not the reality in the former Soviet state, which is home to about 6 million people.

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Why is the zero-case claim unreliable?​

During the early months of the pandemic in 2020, Turkmenistan's authoritarian government faced criticism after it banned WHO officials from entering the country.

That same year, its foreign ministry hit back at a statement from the US embassy in Turkmenistan that acknowledged there were no official reported COVID-19 cases, but said it was aware of reports of local citizens "with symptoms consistent" with the disease. It said the statement was "distorted", "baseless", and "fake".

Comments like these have led some to accuse the government of
COVID-19 denialism
.

READ MORE​


When to expect our next COVID-19 wave — and what could cause cases to spike

In cases where Turkmenistan's state-run media has reported on COVID-19, coverage has focused on events outside the country.

However, during the height of the pandemic, media outside the country reported hospitals were overwhelmed with patients with COVID-19 symptoms,
according to Human Rights Watch
.
Four Turkmenistan men sit on a rug, drinking tea.

Turkmenistan's local vaccination rates are reportedly as high as 70 per cent, according to the World Health Organization. Source: AAP / TASS/Sipa USA
A World Health Organization spokesperson told SBS News in a statement that the global health body was yet to receive any COVID-19 case reports from Turkmenistan.

"We rely on health authorities to inform us of confirmed cases, as per their obligations under the International Health Regulations," the statement read.

"To date, Turkmenistan has not reported any cases of COVID-19."

The spokesperson said that Turkmenistan has "taken measures" to include COVID-19 vaccines into routine vaccination schedules and that, as of August 2023, the government had reported almost 16.8 million vaccine doses had been administered — covering an estimated 60 to 70 per cent of the total population.

Turkmenistan's southern neighbour, Iran, has reported at least 7.6 million cases and 146,000 deaths, according to WHO's March figures.

Its other neighbours, including Kazakhstan, Afghanistan, and Uzbekistan, have also recorded millions of cases.

North Korea changes position on COVID-19​

It took North Korea, ruled by dictator Kim Jong-un, about two years to declare a COVID-19 case after the pandemic was declared in March, 2020.

The hermit kingdom's claims of having no cases for a long period were questioned given that it neighbours China and South Korea, which had early outbreaks.
 
 

US flu, COVID, RSV activity continues to recede​

News brief

April 5, 2024
Lisa Schnirring
Topics

COVID-19

Influenza, General

Respiratory Syncytial Virus (RSV)
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Respiratory virus activity in the United States is still elevated but continues to decline, with only 6 jurisdiction reporting high levels, down from 10 the previous week, the Centers for Disease Control and Prevention (CDC) said today in its data updates.
empty nurses station
hxdbzxy / iStockphoto

Several regions below their flu baselines​

Flu markers declined for the third week in a row, following a prolonged rise after the winter holidays, according to the CDC's latest FluView report. Test positivity and hospitalizations declined last week, while overall deaths and outpatient visits for flulike illness remained level. Though the national level remains slightly above the outpatient visit baseline, six parts of the country are now below their regional baselines.
Of respiratory samples that were positive for flu at public health labs, 61.1% were influenza A and 38.9% were influenza B. Of subtyped influenza A samples, half were the 2009 H1N1 strain and half were H3N2. Seven more pediatric flu deaths were reported, raising the season's total to 133. Two were due to influenza, with 5 were caused by influenza B. The CDC confirmed 184 pediatric flu deaths last season.

Lower levels for all COVID, RSV markers​

In its latest updates for COVID, the CDC reported declines in severity indicators (hospitalizations and deaths) as well as early indicators (test positivity and emergency department visits).
Wastewater SARS-CoV-2 detections remain low and declining in most parts of the country, except for a very small rise in the Northeast.
For respiratory syncytial virus (RSV), activity continues to decrease across the country, and 8 of 10 regions are now below the 3% test-positivity threshold, suggesting that the RSV season is ending in those areas.
 

Four years after shelter-in-place, COVID-19 misinformation persists​

By Kwasi Gyamfi Asiedu, KFF Health News
Published: April 7, 2024, 5:53am
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US President-elect Joe Biden speaks at the Queen Theater after a COVID-19 briefing he held Dec. 29, 2020, in Wilmington, Delaware.
US President-elect Joe Biden speaks at the Queen Theater after a COVID-19 briefing he held Dec. 29, 2020, in Wilmington, Delaware. (Brendan Smialowski/AFP via Getty Images/TNS)



From spring break parties to Mardi Gras, many people remember the last major “normal” thing they did before the novel coronavirus pandemic dawned, forcing governments worldwide to issue stay-at-home advisories and shutdowns.
Even before the first case of COVID-19 was detected in the U.S., fears and uncertainties helped spur misinformation’s rapid spread. In March 2020, schools closed, employers sent staff to work from home, and grocery stores called for physical distancing to keep people safe. But little halted the flow of misleading claims that sent fact-checkers and public health officials into overdrive.
Some people falsely asserted COVID’s symptoms were associated with 5G wireless technology. Faux cures and untested treatments populated social media and political discourse. Amid uncertainty about the virus’s origins, some people proclaimed COVID didn’t exist at all. PolitiFact named “downplay and denial” about the virus its 2020 “Lie of the Year.”
Four years later, people’s lives are largely free of the extreme public health measures that restricted them early in the pandemic. But COVID misinformation persists, although it’s now centered mostly on vaccines and vaccine-related conspiracy theories.

PolitiFact has published more than 2,000 fact checks related to COVID vaccines alone.
“From a misinformation researcher perspective, [there has been] shifting levels of trust,” said Tara Kirk Sell, a senior scholar at the Johns Hopkins Center for Health Security. “Early on in the pandemic, there was a lot of: ‘This isn’t real,’ fake cures, and then later on, we see more vaccine-focused mis- and disinformation and a more partisan type of disinformation and misinformation.”
Here are some of the most persistent COVID misinformation narratives we see today:

A Loss of Trust in the Vaccines​

COVID vaccines were quickly developed, with U.S. patients receiving the first shots in December 2020, 11 months after the first domestic case was detected.
Experts credit the speedy development with helping to save millions of lives and preventing hospitalizations. Researchers at the University of Southern California and Brown University calculated that vaccines saved 2.4 million lives in 141 countries starting from the vaccines’ rollout through August 2021 alone. Centers for Disease Control and Prevention data shows there were 1,164 U.S. deaths provisionally attributed to COVID the week of March 2, down from nearly 26,000 at the pandemic’s height in January 2021, as vaccines were just rolling out.
But on social media and in some public officials’ remarks, misinformation about COVID vaccine efficacy and safety is common. U.S. presidential candidate Robert F. Kennedy Jr. has built his 2024 campaign on a movement that seeks to legitimize conspiracy theories about the vaccines. PolitiFact made that its 2023 “Lie of the Year.”

PolitiFact has seen claims that spike proteins from vaccines are replacing sperm in vaccinated males. (That’s false.) We’ve researched the assertion that vaccines can change your DNA. (That’s misleading and ignores evidence ). Social media posts poked fun at Kansas City Chiefs tight end Travis Kelce for encouraging people to get vaccinated, asserting that the vaccine actually shuts off recipients’ hearts. ( No, it doesn’t. ) And some people pointed to an American Red Cross blood donation questionnaire as evidence that shots are unsafe. (PolitiFact rated that False.)
Experts say this misinformation has real-world effects.
A September 2023 survey by KFF found that 57% of Americans “say they are very or somewhat confident” in COVID vaccines. And those who distrust them are more likely to identify as politically conservative: Thirty-six percent of Republicans compared with 84% of Democrats say they are very or somewhat confident in the vaccine.
Immunization rates for routine vaccines for other conditions have also taken a hit. Measles had been eradicated for more than 20 years in the U.S. but there have been recent outbreaks in states including Florida, Maryland, and Ohio. Florida’s surgeon general has expressed skepticism about vaccines and rejectedguidance from the CDC about how to contain potentially deadly disease spread.
The vaccination rate among kindergartners has declined from 95% in the 2019-20 school year to 93% in 2022-23, according to the CDC. Public health officials have set a 95% vaccination rate target to prevent and reduce the risk of disease outbreaks. The CDC also found exemptions had risen to 3%, the highest rate ever recorded in the U.S.

Unsubstantiated Claims That Vaccines Cause Deaths or Other Illness​

PolitiFact has seen repeated and unsubstantiated claims that COVID vaccines have caused mass numbers of deaths.
A recent widely shared post claimed 17 million people had died because of the vaccine, despite contrary evidence from multiple studies and institutions such as the World Health Organization and CDC that the vaccines are safe and help to prevent severe illness and death.
Another online post claimed the booster vaccine had eight strains of HIV and would kill 23% of the population. Vaccine manufacturers publish the ingredient lists; they do not include HIV. People living with HIV were among the people given priority access during early vaccine rollout to protect them from severe illness.
COVID vaccines also have been blamed for causing Alzheimer’s and cancer. Experts have found no evidence the vaccines cause either conditions.

“You had this remarkable scientific or medical accomplishment contrasted with this remarkable rejection of that technology by a significant portion of the American public,” said Paul Offit, director of the Vaccine Education Center at the Children’s Hospital of Philadelphia.
More than three years after vaccines became available, about 70% of Americans have completed a primary series of COVID vaccination, according to CDC figures. About 17% have gotten the most recent bivalent booster.
False claims often pull from and misuse data from the Vaccine Adverse Event Reporting System. The database, run by the CDC and the FDA, allows anybody to report reactions after any vaccine. The reports themselves are unverified, but the database is designed to help researchers find patterns for further investigation.
An October 2023 survey published in November by the Annenberg Public Policy Center at the University of Pennsylvania found 63% of Americans think “it is safer to get the COVID-19 vaccine than the COVID-19 disease” — that was down from 75% in April 2021.

Celebrity Deaths Falsely Attributed to Vaccines​

Betty White, Bob Saget, Matthew Perry, and DMX are just a few of the many celebrities whose deaths were falsely linked to the vaccine. The anti-vaccine film “ Died Suddenly “ tried to give credence to false claims that the vaccine causes people to die shortly after receiving it.
Céline Gounder, editor-at-large for public health at KFF Health News and an infectious disease specialist, said these claims proliferate because of two things: cognitive bias and more insidious motivated reasoning.
“It’s like saying ‘I had an ice cream cone and then I died the next day; the ice cream must have killed me,” she said. And those with preexisting beliefs about the vaccine seek to attach sudden deaths to the vaccine.
Gounder experienced this personally when her husband, the celebrated sports journalist Grant Wahl, died while covering the 2022 World Cup in Qatar. Wahl died of a ruptured aortic aneurysm but anti-vaccine accounts falsely linked his death to a COVID vaccine, forcing Gounder to publicly set the record straight.

“It is very clear that this is about harming other people,” said Gounder, who was a guest at United Facts of America in 2023. “And in this case, trying to harm me and my family at a point where we were grieving my husband’s loss. What was important in that moment was to really stand up for my husband, his legacy, and to do what I know he would have wanted me to do, which is to speak the truth and to do so very publicly.”

Out-of-Control Claims About Government Control​

False claims that the pandemic was planned by government leaders and those in power abound.
At any given moment, Microsoft Corp. co-founder and philanthropist Bill Gates, World Economic Forum head Klaus Schwab, or Anthony Fauci, former director of the National Institute of Allergy and Infectious Diseases, are blamed for orchestrating pandemic-related threats.
In November, Rep. Matt Rosendale (R-Mont.) falsely claimed Fauci “brought” the virus to his state a year before the pandemic. There is no evidence of that. Gates, according to the narratives, is using dangerous vaccines to push a depopulation agenda. That’s false. And Schwab has not said he has an “agenda” to establish a totalitarian global regime using the coronavirus to depopulate the Earth and reorganize society. That’s part of a conspiracy theory that’s come to be called “ The Great Reset “ that has been debunkedmanytimes.

The United Nations’ World Health Organization is frequently painted as a global force for evil, too, with detractors saying it is using vaccination to control or harm people. But the WHO has not declared that a new pandemic is happening, as some have claimed. Its current pandemic preparedness treaty is in no way positioned to remove human rights protections or restrict freedoms, as one post said. And the organization has not announced plans to deploy troops to corral people and forcibly vaccinate them. The WHO is, however, working on a new treaty to help countries improve coordination in response to future pandemics.

KFF Health News is a national newsroom that produces in-depth journalism about health issues and is one of the core operating programs of KFF — the independent source for health policy research, polling and journalism.
 

FDA Authorizes COVID Drug Pemgarda for High-Risk Patients​


BY CARRIE MACMILLAN APRIL 5, 2024
A Yale Medicine expert explains the significance of a new pre-exposure prophylaxis (PrEP) medication to protect immunocompromised people against COVID-19.
woman removing mask after taking Pemgarda, which protects against COVID


The Food and Drug Administration (FDA) granted an emergency use authorization (EUA) to a medicine meant to protect certain immunocompromised people against COVID-19.
The medicine, pemivibart (brand name Pemgarda™), is for people who are at least 12 years of age, weigh more than 88 pounds, and are moderately to severely immunocompromised.
An EUA is a tool the FDA uses to expedite the availability of drugs, vaccines, and other products during a public health emergency. While the public health emergency for COVID officially expired in May 2023, the FDA can still issue EUAs related to it.
“This medication provides important protection for the immunocompromised, a population that is more likely to have serious COVID illness and a higher mortality rate,” says Scott Roberts, MD, a Yale Medicine infectious diseases specialist.
Being immunocompromised means your immune system doesn’t work as well as it should to protect against infection because of a medical condition, such as cancer, that weakens immune function or because you receive medicines or treatments, such as immunotherapy, that suppress the immune system.
“The population identified as moderately to severely immunocompromised includes solid organ transplant recipients, stem cell transplant recipients, and those who are on chemotherapy for cancers such as lymphoma and leukemia, among many others,” Dr. Roberts explains. The Centers for Disease Control and Prevention (CDC) provides a list. Approximately 3% of adults in the United States are immunocompromised.
“This group is also less likely to build enough protection against COVID after vaccination. For these patients, the pandemic is not over,” says Dr. Roberts. “Hopefully, this new treatment will help the vulnerable feel safer.”
Below, we talk more about Pemgarda with Dr. Roberts.

Why isn’t COVID vaccination as effective in immunocompromised individuals?​

Those who are not immunocompromised most likely have a strong mix of “hybrid” immunity to COVID at this point, both from vaccination and natural infection, Dr. Roberts explains.
“Most people should not be concerned when a new COVID variant arises because even if it bypasses some of their protection, it's not going to bypass all of it,” Dr. Roberts says. “But some immunocompromised people do not have that luxury. Any COVID infection is going to hit them the hardest. And vaccination is still the best tool we have to offer for the prevention of severe COVID.”
However, this drug is a new tool that can help immunocompromised patients feel safe going about daily activities as many other people do at this phase of the pandemic, he adds.

How does Pemgarda work?​

Pemgarda is a type of medicine called pre-exposure prophylaxis (PrEP), which is taken to prevent COVID infection. Anyone with COVID—or who has a known recent exposure to someone with a COVID infection—cannot take Pemgarda.
Paxlovid and Remdesivir, conversely, are meant to be taken after a known COVID infection and are for anyone deemed high-risk for serious illness, including those who are immunocompromised.
Pemgarda is a type of monoclonal antibody (mAb), a drug therapy that uses antibodies made in a laboratory. These antibodies attach to the spike protein of SARS-CoV-2, the virus that causes COVID-19, and prevent the virus from entering the body’s cells.
“Despite vaccination, many immunocompromised patients are still unable to generate the antibodies necessary to block this entry; Pemgarda serves as a tool to increase SARS-CoV-2-specific antibodies to levels seen in nonimmunocompromised individuals after vaccination,” says Dr. Roberts.
It is given as an infusion in a medical setting and takes about an hour to complete. Patients can get a dose of the medication as often as every three months.

Is this the first preventive drug for COVID?​

A previous mAb treatment, Evusheld™, was authorized by the FDA in 2021 to prevent COVID in immunocompromised patients. However, the medication proved ineffective against newer COVID variants and was taken off the market in January 2023.
Pemgarda is the only COVID PrEP drug on the market.

How effective is Pemgarda against COVID?​

Pemgarda was granted an EUA based on data from an ongoing Phase 3 clinical trial, as well as data from previous clinical trials of a similar monoclonal antibody treatment.
In the trials, Pemgarda reduced the risk of developing symptomatic COVID-19 by 70%, according to Invivyd, the company that makes the drug. The studies were done when the JN.1 subvariant was circulating. JN.1 is still the predominant coronavirus subvariant.

Is Pemgarda safe?​

In the trial, 623 participants received at least one dose of the drug. The most common side effects included skin reactions at the infusion site, cold and flu-like illness, headache, fatigue, and nausea. Four people experienced anaphylaxis (a severe allergic reaction).
“For patients who are worried about the trade-off, I think it requires a risk-benefit analysis,” says Dr. Roberts. “I think in most cases the benefit is going to outweigh the risk of anaphylaxis, especially if doctors can mitigate it by having medications such as an Epi-pen there in case a patient does have a severe allergic reaction.”

Where and when can patients get Pemgarda?​

Immunocompromised people who are interested in taking Pemgarda should talk to their doctor. “It might be better for some patients to talk to a specialist first—for instance, if an individual has cancer, it might be best for them to talk to their oncologist about whether this drug is right for them,” Dr. Roberts advises.
The medication is expected to be available in April. The price has not yet been set, but Medicare and private insurance plans are expected to cover it, according to news reports.
 

Researchers say more support, education needed to help B.C. long-COVID patients​

Darrian.png

By Darrian Matassa-Fung Global News
Posted April 5, 2024 4:22 pm
Updated April 5, 2024 8:49 pm
2 min read
Click to play video: 'Report calls for more research and support for long COVID patients'





More than 3.5 million Canadians have experienced symptoms of long COVID but many people still don't believe it's real. As Travis Prasad reports, a new SFU study is calling for more education, investment and support for those suffering from the lingering effects of COVID.
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Better long-COVID awareness, education and support are needed for patients, according to Simon Fraser University researchers who conducted a study on the topic.
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More education for health-care workers, including doctors and nurses, is one of the recommendations made in a report done by the SFU-based Pacific Institute on Pathogens, Pandemics and Society.
Click to play video: 'SFU Long COVID study'


4:23SFU Long COVID study
The report includes findings from two focus groups of unpaid caregivers, professional care providers, long-COVID researchers and people living with long COVID, identified as “longhaulers”.
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“It’s an invisible and new condition,” said Kayli Jamieson, a longhauler who co-led the focus groups as part of a larger study with Kaylee Byers, an assistant professor in SFU’s Faculty of Health Sciences. “Many people don’t believe that long COVID is real or exists. Unfortunately, that permeates through the healthcare system.”
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Long COVID is a multi-systemic condition that can begin weeks after a COVID-19 infection and can last for years, researchers said.
Those living with long COVID often need to take leave from work to rest and manage their symptoms.
Click to play video: 'Long COVID patients decry government closure of in-person clinics'


2:12Long COVID patients decry government closure of in-person clinics
According to Statistics Canada, more than 3.5 million Canadian adults have experienced long COVID symptoms, with 40 per cent of those saying they had difficulties accessing health care.
Researchers said despite hundreds of studies into long COVID, there are no standard cures or treatments that have been approved.
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“We want to be visible, but we’re increasingly being made invisible. As one unpaid caregiver in our study said, ‘I think there needs to be a cultural shift in terms of people believing that long COVID exists,’” Jamieson said.
Jamieson caught COVID-19 in 2021 and has been dealing with long COVID symptoms ever since.
She was a master’s student at the time and had two jobs. Due to her symptoms, she had to go on medical leave.
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“It’s a drastic change,” she said. “The cognitive difficulties … I wasn’t even able to understand my own previous work when I was reading it and the fatigue is disabling. “There are so many triggers, like even reading an email, or socializing and that could just about be enough to leave you bed bound due to post-exertional malaise.”
Along with brain fog and exhaustion, Jamieson’s symptoms included rashes, tinnitus, chest pains, shortness of breath and tremors.
In the report’s conclusion, it found that greater investments need to be made into the public health sector to find evidence-based pathways for care.
“As the pandemic continues, long COVID needs to be imminently addressed at all institutional levels, especially given its potential to be a “mass-disabling event” with resulting socio economic ramifications,” the report said.
“Significant monetary investments need to be made to provide supports, accessible information, and produce research advancing patient rehabilitation.”
 

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Weekly Ontario Update for Friday, April 5, 2024:

Public Health Ontario has further reduced the amount of data available to the public. In addition, Health Canada has stopped reporting hospitalization data as some provinces are no longer tracking COVID hospitalizations.

Unless indicated otherwise, information in this update includes data from Sunday, March 24 to Saturday, March 30, so data is delayed.

Data relating to deaths is even further delayed as cause of death is taking MONTHS to be determined. So recent deaths are far WORSE that are reported.

  • Recent cases: 526 (- 82 compared to last week) Estimates suggest that the actual number of new cases could be more than 10 times higher than what is being reported due to limited eligibility for testing!
  • Weekly positivity rate: 4.2% (- 1.7% since last week)
    🙂
  • Recent deaths: 4 (1 FEWER than last week) - Total deaths: no longer being reported Recent deaths are a lagging indicator of the current level of new cases. Deaths are underreported because they are based on date of death and by the time the cause of death is reported, it is no longer considered recent!
  • Average daily hospital bed occupancy: 246* (- 33 since last week week). *Please interpret the COVID-19 hospitalization data with caution as not all centers are reporting..
  • The completeness of COVID-19 hospitalization data, which PHO obtains from the provincial Case and Contact Management database (CCM), has been declining over the course of the 2023-24 surveillance period.
Full list of those eligible for testing can be found here (updated): https://www.ontario.ca/.../covid-19-testing-and-treatment...
Sources: Total cases, total deaths, testing levels and wastewater levels: https://www.publichealthontario.ca/.../Respiratory-Virus...
Some additional COVID stats and info: https://twitter.com/MoriartyLab
 

Severe COVID leads to higher risk of pulmonary fibrosis: research​

Condition is usually fairly mild but scarred lungs can increase severity, respirologist says​

CBC News · Posted: Apr 08, 2024 7:00 AM EDT | Last Updated: 10 hours ago
Doctor Daniel Marinescu, a respirologist, points to a patient's CT scan. He points out scarring on the lungs of the patient which can occur after long COVID.

Respirologist Dr. Daniel Marinescu examines a patient's CT scan. He points out scarring on the lungs that can occur after severe cases of COVID-19. (CBC News)

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For Vancouver resident Farrell Eckman, having a long conversation or attending a workout class without breaking into coughs is a major accomplishment.
The 50-year-old is one of many people who researchers say developed pulmonary fibrosis — a condition that thickens the tissue in lungs and can affect breathing — after experiencing a severe case of COVID-19.
In January 2022, Eckman was admitted to Vancouver General Hospital because she was having trouble breathing along with flu-like symptoms.
"I spent over a month in ICU. I was on a ventilator. Not once, but twice. [My family] thought they were gonna lose me," she recalled. "It was the scariest time we've ever been through."
Farrell Eckman, who has been diagnosed with pulmonary fibrosis following two bouts with COVID, shows an air compressor that is kept in her home.

Farrell Eckman, who has been diagnosed with pulmonary fibrosis after she was hospitalized with COVID, at home beside an air compressor. Eckman occasionally uses oxygen to help deal with shortness of breath brought on by pulmonary fibrosis. (CBC News)
Eckman's time in hospital was caused by her second bout of COVID. She had received three vaccines for the coronavirus that causes the disease.
While she eventually recovered and was released to go home along with six litres of oxygen, which is the maximum amount a patient can be discharged with. Eckman was later diagnosed with pulmonary fibrosis, caused by the toll that COVID took on her lungs.
"The damage that was sustained to my lungs from COVID pneumonia was severe. They've looked at my lungs numerous times. I don't know if I'll ever fully recover. I'm functioning, which is tremendous. But I could possibly be dealing with this for the rest of my life."
A meta-analysis published in the Annals of Medicine & Surgery in April 2022 found almost 45 per cent of recovered COVID-19 patients developed pulmonary fibrosis, and those patients often suffered persistent symptoms such as coughing, chest pain and fatigue.
The research also drew a link between severity of COVID-19 symptoms and severity of consequent pulmonary fibrosis.
It's something Daniel Marinescu, a respirologist at Vancouver General Hospital, says he is seeing more often, adding that patients are more prone to developing pulmonary fibrosis depending on how severe scarring of their lung tissue is.
Doctor Daniel Marinescu and patient Farrell Eckman meet in an office at Vancouver General Hospital.

Dr. Daniel Marinescu and Farrell Eckman meet at Vancouver General Hospital. (CBC News)
Marinescu says he's seen "several dozen" of these cases.
"Most of the time it is a fairly mild disease and most of the time people slowly get better over months and years," he said. "But sometimes people take a big hit if they're in the ICU for a long time or on the ventilator for a long time."
Janet Pope, a rheumatologist and professor of medicine at Western University in London, Ont., says while research is limited, factors like age and smoking could affect the likelihood of patients developing the condition.
"We know that COVID pneumonia can cause pulmonary fibrosis. Not in most people who get COVID pneumonia, but if it's more severe, older age groups, more severe inflammation of the lungs from COVID," she said.
Pope adds patients may feel frustrated with their symptoms, but recommends sharing concerns with health-care professionals.
"They would take a stethoscope and listen to the bottom of the lungs. It takes four seconds to do. If they hear what we call 'crackles' then they can do a chest X-ray," she said.
"Have a listen to people if they say they're short of breath, if they're coughing, if they have a cold that's not improving," she advises.
For Eckman, recovery remains a constant in her life. She says she works daily on improving her breathing, and does pilates regularly. However, she still occasionally has to use oxygen at night to help with her breathing.
"I just passed my two-year anniversary. I'm still dealing with it. It's an ongoing process," she said.
 

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