SARS-CoV-2/COVID related discussion

Yommie

Elite Member
Oct 2, 2013
55,190
36,697
Country of Origin
Country of Residence

Why are people suddenly getting COVID-19 this summer? Insight into the uptick.​

Eduardo Cuevas
USA TODAY

Just as summer gatherings begin, Americans are also catching COVID-19 again.
Cases predictably rose, in upticks, during the winter with more people indoors. They are also increasing as experts expected at the start of summer. Centers for Disease Control and Prevention data shows small jumps in hospitalizations and deaths and slight increases in new cases. This latest rise in cases shows how the virus has persisted four years since the start of the COVID-19 pandemic.
“When you begin to see a pattern, you then might say it’s becoming endemic,” Dr. Jessica Justman, a professor of epidemiology and medicine at Columbia University, told USA TODAY. “When something is endemic, that does not mean it’s going away. That means it’s staying around.”

Another common endemic disease Americans have learned to prevent routinely is seasonal flu.
SARS-CoV-2, like any virus, is constantly mutating so it can infect more people and survive. New variants and sub-variants expand outward like branches from trees, each with different mutations seeking to adapt. As the changes happen, health experts and officials have responded with vaccines and other protections to reduce the risk of serious illness or overwhelmed health systems.

CDC warns that new COVID-19 variants, nicknamed FLiRT, found in wastewater


COVID-19 increases​

The upticks from the latest sub-variants are nowhere near levels the U.S. experienced in 2020, or when the omicron variant began to drive cases and deaths across the globe in 2021. Hospitalizations and emergency room visits are far less frequent this season than in December. Deaths have not reached the levels of this winter when more than 2,000 people died from COVID-19 each week in January. In the latest CDC estimates as of June 15, fewer than 150 people died of COVID-19.

Cases are driven by consistent upticks in a collection of sub-variants known as FLiRT, named for the mutations’ technical names. FLiRT derives from the JN.1 variant, descended from omicron, which dominated cases until the spring, according to the CDC’s Nowcast loose estimates of circulating variants. Now, FLiRT increasingly causes cases in the U.S. The largest is the KP.3 sub-variant which accounts for about a third of cases, followed by KP.2, and KP.1.1, CDC data showed. LB.1, derived from JN.1, also accounts for a substantial portion of estimated circulating variants.

The western U.S. and Hawaii have experienced increases in recent weeks, CDC data showed. However, wastewater samples – a surveillance tool to detect COVID-19’s spread – across the U.S. appear to show increases in the virus’ spread.
Michael Osterholm, director of the University of Minnesota’s Center for Infectious Disease Research and Policy, said a portion of the new cases involve the FLIRT variant, however, he noted that the U.S. lacks good surveillance this late in the pandemic.
“It’s fair to say that there is an increase,” he said. “What we don’t know yet is how much it’s going to be.”




Is FLiRT more transmissible?​

FLiRT may be more transmissible, partially because of mutations that make it easier to shield the virus from antibodies, according to Andy Pekosz, a professor of molecular biology and immunology at Johns Hopkins Bloomberg School of Public Health, in a Q&A in May. But it doesn’t seem to cause more severe illness or present different symptoms.

Vaccines provide protection against COVID-19, though they may wane over time. The last vaccine in late 2023 targeted the XBB.1.5 variant. In February, the CDC updated its guidance for people 65 and older to get a booster of the current vaccine. In early June, a Food and Drug Administration advisory panel recommended vaccine makers to target the JN.1 lineage. A new round of vaccines is expected in the late summer or early fall.
People experiencing respiratory symptoms should reduce the spread of the virus by staying home. They should also contact health providers for treatment if they’re at serious risk of illness. Experts continue to recommend wearing a mask and distancing to reduce transmission of COVID-19.
 

Yommie

Elite Member
Oct 2, 2013
55,190
36,697
Country of Origin
Country of Residence

New CDC data shows up to 39 states are seeing a rise in Covid cases​


 

Yommie

Elite Member
Oct 2, 2013
55,190
36,697
Country of Origin
Country of Residence

Heat related illness, summer COVID uptick and WHO weight loss drug warning for fake Ozempic online​


 

Yommie

Elite Member
Oct 2, 2013
55,190
36,697
Country of Origin
Country of Residence

40 COVID Deaths in Past Week as Cases Ramp Up in Taiwan | TaiwanPlus News​


 

Yommie

Elite Member
Oct 2, 2013
55,190
36,697
Country of Origin
Country of Residence

How do I know if I have Covid? Only a test can say for sure.​

Gone are the days that a fever was a sure sign of Covid. As the virus mutates and infections rise again, Covid symptoms vary widely from person to person.

Positive Covid-19 test

The double red line is not a welcome sight. Covid cases are rising, but symptoms vary widely from person to person.dpa via Getty Images

June 27, 2024, 11:25 AM EDT
By Erika Edwards

As the nation enters yet another summer Covid wave, doctors say it’s nearly impossible to diagnose a person with the illness based on symptoms alone.
“Every week, we test someone for Covid who I didn’t think had it who tests positive. Then we have others who I’m pretty sure have Covid who test negative,” said Dr. Steven Furr, a family physician in Jackson, Alabama, and president of the American Academy of Family Physicians.

“It’s really hard to separate Covid from any other respiratory illness right now,” he said.
Covid patients, Furr and other doctors said, are showing up at clinics with a spectrum of symptoms.
“Some people have a very classic sore throat, runny nose, cough and low-grade fever,” said Dr. Paul Sax, the clinical director of the division of infectious diseases at Brigham and Women’s Hospital and a professor of medicine at Harvard Medical School. “In others, it’s mostly nausea and diarrhea with very minimal respiratory symptoms. It can vary from A to Z and beyond.”
Dr. Bernard Camins, medical director for infection prevention at the Mount Sinai Health System in New York City, has noted the same trend.
Without a test, “you can’t tell nowadays whether it’s a cold or Covid,” Camins said.
As of mid-June, the Centers for Disease Control and Prevention said it appeared that Covid infections were rising in 39 states. Covid-related emergency department visits, hospitalizations and deaths are all up as well.

Covid keeps changing to be more contagious​

The diagnostic landscape is dramatically different from 2020, when a fever was considered a strong indication of Covid.

“That’s not really a major sign anymore,” Furr said. “Now, there’s no one symptom where you say, ‘Hey, you probably have Covid.’ Without a test, we’re not going to know for sure.”
There are multiple reasons for the change. Nearly everyone’s immune system has been exposed to the virus multiple times through vaccination, infection or both.
“That appears to ameliorate the severity of the disease over time,” Sax said. “Recurrent infections are typically milder than first-time infections — not always, but usually.”
What’s more, the virus itself has changed again and again. The latest omicron subvariants that account for a majority of cases — KP.3, KP.2 and LB.1 — are adept at making people sick, but usually not too sick.
LB.1 in particular “has the potential to infect some people more easily based on a single deletion in a spike protein,” a CDC spokesman said in an email. “However, there is currently no evidence that LB.1 causes more severe disease.”

1719357716376_nn_emc_covid_summer_rise_240625_1920x1080-mpmiu1.jpg


Earlier this month, the Food and Drug Administration told vaccine makers to target the KP.2 strain for this fall’s round of Covid shots. On Thursday, a CDC advisory panel is scheduled to discuss who should get them.

The experts are at least likely to recommend updated Covid vaccines for people most at risk of complications: older adults 65 and above and people who are severely immunocompromised, such as organ transplant recipients.
People with underlying conditions are also likely to be on the list. Sax said that many people hospitalized with Covid now have other chronic illnesses, such as congestive heart failure.
“Their heart isn’t pumping very well” to begin with, he said. “Then along comes Covid, and their congestive heart failure gets worse.”

When to test, and when to isolate?​

Given the array of possible Covid symptoms, it may be difficult to know when to take a test. And tests may give false negatives if taken too early.
“We still have cases who test negative on initial testing and test positive a day or two later,” said Dr. Abraar Karan, an infectious disease fellow at Stanford Medicine in California. Karan said that’s not surprising because “the amount of virus present has to increase enough in the sample for it to be detectable.”
Antigen tests — the ones many Americans have squirreled away at home — are especially susceptible to false negatives when people first start to feel sick.
“Rapid tests often aren’t positive on the first day of symptoms,” Sax said. “It often takes day two or three or four” for the test to pick up enough of the virus for a positive result.
If a person does test positive, there is no longer a mandatory five-day isolation period, the CDC said this spring in updated guidance.
Instead, the CDC advises that people stay home when they’re symptomatic, but return to school, work and social activities once they’re feeling better.
“Once the symptoms resolve or are all but done, there really are no rules about stopping isolation,” Sax said.
 

Yommie

Elite Member
Oct 2, 2013
55,190
36,697
Country of Origin
Country of Residence

Peters Asks Experts About COVID Origin Debate: What 'Specific Information' Do We Need From China?​


 

Yommie

Elite Member
Oct 2, 2013
55,190
36,697
Country of Origin
Country of Residence

How much should we worry each time a new COVID-19 variant arises? | commentary​


 

Users who are viewing this thread

Top